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Science 375(6586):12541261 Jensen M, Engert A, Weissinger F, Knauf W, Kimby E, Poynton C, Oliff IA, Rummel MJ, Osterborg A (2008) Phase I study of a novel pro-apoptotic drug R-etodolac in patients with B-cell chronic lymphocytic leukemia

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for long-term storage keep it frozen, away from light and moisture

However, their persistence in the environment raises serious toxicological concerns, such as lung toxicity (inflammation, fibrosis, and respiratory dysfunction), skin toxicity (allergic reactions and dermatitis), liver damage (oxidative stress and lipid peroxidation), kidney toxicity (nephrotoxicity and filtration interference), and cardiovascular problems (endothelial dysfunction and arterial plaque formation)